Kuwait Variome

Example: Gene HNF1B , Rsid rs41290504, Variant 10:101639877-A-C, Phenotype BMI and SMYD4

A compendium of genetic variants through exome sequencing, genome-wide genotyping and imputation on cohorts of different disease types. These variants were compiled and systematically annotated using results of genetic association studies for metabolic trait

Datasets

T1DM dataset

Presents 216489 variants identified through whole-exome sequencing of 63 Arab individuals afflicted with Type 1 diabetes.

MODY dataset

Presents 169559 variants identified through whole-exome sequencing of 47 Arab individuals afflicted with MODY.

T2DM dataset

Presents 113053 high-quality variants identified through whole-exome sequencing of 114 Arab individuals diagnosed for Type 2 diabetes.

Non-diabetic dataset

Presents 130953 high-quality variants identified through whole-exome sequencing of 168 Arab individuals NOT diagnosed for diabetes.

Kuwait population exome variants dataset

199502 high-quality variants identified through whole-exome sequencing of 474 individuals not tested for diabetes.

Kuwait population GWAS variants dataset

This dataset comprises of 118,793 variants identified through genome-wide genotyping of 1434 Arab individuals using the Illumina CardioMetaboChip, 674,131 variants identified through genome-wide genotyping of 1298 Arab individuals using the Illumina OmniExpress BeadChip, imputed OmniExpress dataset of 6.2 million markers and an imputed MetaboChip dataset of 1.52 million markers.